Mystics like Nostradamus have regularly tried to calculate the end of the world. HG Wells tried to develop a science of forecasting and famously depicted the far future of humanity in his book The Time Machine. Other writers built other long-term futures to warn, amuse or speculate. Nevertheless, human activity has been steadily shaping the future of our planet. And even though we are far from controlling natural disasters, we are developing technologies that may help mitigate, or at least, deal with them. Are there scenarios where human beings are unable to change or improve in order to save us?